Known Issues

ISSUE

IUCLID import fails in some cases

IUCLID Import fails with a “Object reference not set to an instance of an object” during IUCLID import of chemicals that have Identifier that is not accompanied by Identity in the Synonyms section:

tb issue iuclid import 300x248 - IUCLID import fails in some cases

FIX

There are two possible fixes for this:
  1. Fix the source data, by removing Synonym entries that have Identity defined, but have no Identifier attached
  2. Use an updated assembly that can be downloaded from here. It should replace a file with the same name in the QSAR Toolbox Desktop Client’s bin folder, e.g. C:\Program Files (x86)\QSAR Toolbox\QSAR Toolbox 4.5\Toolbox Client\bin\

ISSUE

Toolbox Client starts, displays splash screen, but the application window disappears

Toolbox Client starts, displays splash screen, but the application window disappears after that, leaving a process in the Task Manager.

Alternative manifestation:  Toolbox Server may display error: System.TypeInitializationException: The type initializer for ‘<Module>’ threw an exception. —> System.BadImageFormatException: Could not load file or assembly

FIX

Follow the instructions in the following document: Toolbox Client starts but hides after the splash screen (BadImage)

ISSUE

You have a previous deployment of PostgreSQL server but don’t know the password for it. You need to reset the PostgreSQL password

FIX

Follow the instructions in this document.

ISSUE

The Toolbox Server cannot connect to the PostgreSQL database when the server application and PostgreSQL are deployed on separate machines

The error log shows:

Npgsql.PostgresException: 28000: no pg_hba.conf entry for host "", user "qsartoolbox", database "EpiReports42".

This happens when the QSAR Toolbox Server is installed on one machine and the PostgreSQL database is deployed on a different machine. The PostgreSQL server would need to be configured to allow access to the deployed databases for the QSAR Toolbox Server Application.

FIX

  1. Go to PostgreSQL server's Data folder (default folder C:\Program Files\PostgreSQL\9.6\data) and open the pg_hba.conf file.
  2. Add a line to the bottom of the file changing <ToolboxServerHost> to the IP address or hostname of the computer than is hosting the QSAR Toolbox Server.
    host all qsartoolbox md5
  3. Restart the PostgreSQL service.
  4. Restart the QSAR Toolbox Server application/service.

Download Installation Package

QSAR Toolbox Installer version 4.5 SP1